Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP4C All Species: 40.91
Human Site: T293 Identified Species: 64.29
UniProt: P60510 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P60510 NP_002711.1 307 35080 T293 F E A A P Q E T R G I P S K K
Chimpanzee Pan troglodytes XP_001148385 265 30391 T252 Y K W H F N E T V L T V W S A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_858953 324 36761 T310 F E A A P Q E T R G I P S K K
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q5BJ92 307 35049 T293 F E A A P Q E T R G I P S K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505222 306 34933 T292 F E A A P Q E T R G I P S K K
Chicken Gallus gallus P48463 309 35545 G296 F D P A P R R G E P H V T R R
Frog Xenopus laevis Q6IP91 307 35104 T293 F E A A P Q E T R G I P S K K
Zebra Danio Brachydanio rerio A9JRC7 307 35078 T293 F E A A P Q E T R G I P S K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76932 307 35323 S293 F E A A P Q E S R G I P S K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XW79 333 37341 N319 F E A A P Q E N R G A P A K K
Sea Urchin Strong. purpuratus XP_799172 307 35031 V293 F E A A P Q E V R G I P A K K
Poplar Tree Populus trichocarpa XP_002317353 305 34758 S291 F D A A P Q E S R G A P S K K
Maize Zea mays NP_001170721 307 34933 S293 F E A A P H E S R G V P A K R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P48528 305 34707 S291 F D A A P Q E S R G A L A K K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48580 327 37273 G314 F D P C P R A G E P M V S R R
Conservation
Percent
Protein Identity: 100 86.3 N.A. 94.7 N.A. N.A. 99.6 N.A. 91.2 66 99 98 N.A. 91.5 N.A. 74.7 93.4
Protein Similarity: 100 86.3 N.A. 94.7 N.A. N.A. 99.6 N.A. 92.5 81.2 99.6 99.6 N.A. 96.4 N.A. 82.5 97
P-Site Identity: 100 13.3 N.A. 100 N.A. N.A. 100 N.A. 100 20 100 100 N.A. 93.3 N.A. 80 86.6
P-Site Similarity: 100 26.6 N.A. 100 N.A. N.A. 100 N.A. 100 53.3 100 100 N.A. 100 N.A. 86.6 93.3
Percent
Protein Identity: 82 81.4 N.A. 82 N.A. 60.8
Protein Similarity: 89.9 90.8 N.A. 90.5 N.A. 75.8
P-Site Identity: 80 66.6 N.A. 66.6 N.A. 20
P-Site Similarity: 93.3 93.3 N.A. 86.6 N.A. 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 80 87 0 0 7 0 0 0 20 0 27 0 7 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 27 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 67 0 0 0 0 87 0 14 0 0 0 0 0 0 % E
% Phe: 94 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 14 0 80 0 0 0 0 0 % G
% His: 0 0 0 7 0 7 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 54 0 0 0 0 % I
% Lys: 0 7 0 0 0 0 0 0 0 0 0 0 0 80 74 % K
% Leu: 0 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 14 0 94 0 0 0 0 14 0 74 0 0 0 % P
% Gln: 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 14 7 0 80 0 0 0 0 14 20 % R
% Ser: 0 0 0 0 0 0 0 27 0 0 0 0 60 7 0 % S
% Thr: 0 0 0 0 0 0 0 47 0 0 7 0 7 0 0 % T
% Val: 0 0 0 0 0 0 0 7 7 0 7 20 0 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _